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Nipoppy MCP Server

An interface for the Nipoppy neuroimaging framework that enables AI agents to list files and manage clinical datasets. It facilitates interaction with neuroimaging data organized according to the Brain Imaging Data Structure (BIDS) standard.

Updated
Jan 28, 2026

Nipoppy MCP Server

A Model Context Protocol (MCP) interface for the Nipoppy neuroimaging dataset framework. This server exposes a simple tool through MCP, allowing AI agents to list files in directories.

What is Nipoppy?

Nipoppy is a lightweight framework for standardized organization and processing of neuroimaging-clinical datasets. It follows the Brain Imaging Data Structure (BIDS) standard and provides tools for managing datasets and processing pipelines.

What is MCP?

The Model Context Protocol (MCP) is a standardized protocol that allows AI applications (LLMs) to access external tools and resources through a consistent interface. This server exposes a file listing tool as an MCP tool.

Features

This MCP server provides the following tool:

  • list_files: List files in a given directory

Installation

Prerequisites

  • Python 3.8 or higher

Install the package

# Clone the repository
git clone https://github.com/nipoppy/mcp.git
cd mcp

# Install dependencies
pip install -e .

Usage

Running the MCP Server

The server can be run in different modes depending on your use case:

1. STDIO Mode (for local desktop apps like Claude Desktop)

# Set the dataset root (optional, defaults to current directory)
export NIPOPPY_DATASET_ROOT=/path/to/your/nipoppy/dataset

# Run the server
python -m nipoppy_mcp.server
```bash
# Run the server
python -m nipoppy_mcp.server

2. Configure with Claude Desktop

Add to your Claude Desktop configuration file (~/Library/Application Support/Claude/claude_desktop_config.json on macOS):

{
  "mcpServers": {
    "nipoppy": {
      "command": "python",
      "args": ["-m", "nipoppy_mcp.server"]
    }
  }
}

Using the Tool

Once connected to an MCP-compatible client, you can use natural language to list files in directories:

Example queries:

  • "List files in /path/to/directory"
  • "What files are in my home directory?"

Development

Running Tests

# Install development dependencies
pip install -e ".[dev]"

# Run tests
pytest

Project Structure

mcp/
├── nipoppy_mcp/
│   ├── __init__.py
│   └── server.py          # Main MCP server implementation
├── tests/                 # Test files
├── pyproject.toml        # Project configuration
└── README.md

Contributing

Contributions are welcome! This is a Brainhack 2026 project. Please feel free to submit issues and pull requests.

License

MIT License - see LICENSE file for details.

Resources

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